Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation
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چکیده
منابع مشابه
Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation
Glomerular podocytes are able to transdifferentiate under disease conditions, acquire de novo immune phenotypes and behave as immunocompetent cells, like phagocytes or antigen-presenting cells. Upon stimulation with lipopolysaccharide (LPS), a prototypical pathogen-associated molecular pattern, podocytes demonstrated de novo expression of a variety of NFkB-dependent immune molecules that are pi...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.19917